Alexis T. Thompson
Chesapeake
Summary
PhD candidate specializing in molecular dynamics simulations, protein modeling, and computational biophysics. Experienced in modeling protein–ligand interactions, analyzing large datasets, and collaborating on interdisciplinary research teams in both academic and federal lab environments. Proficient in industry-relevant tools including AMBER, AutoDock Vina, and Python-based workflows, with a strong focus on translating computational results into actionable scientific insights.
Overview
8
8
years of professional experience
Work History
Research Assistant
U.S. Army Corps of Engineers
05.2024 - Current
- Collaborated with chemists, engineers, and domain experts to create computational and experimental solutions addressing project challenges
- Analyzed complex scientific data to inform decision-making and enhance project outcomes
- Contributed to applied research projects that advanced environmental and engineering missions
Graduate Researcher (Computational Chemistry)
Old Dominion University
08.2020 - Current
- Modeled protein–ligand interactions to assess binding affinity and structural behavior
- Executed molecular dynamics simulations to evaluate protein structure, stability, and function, enhancing understanding of molecular behavior
- Interpreted large simulation datasets to identify key molecular trends, informing subsequent research directions
- Utilized visualization tools to communicate findings to technical and non-technical stakeholders
Preparatory Teaching Assistant (Lab Operations & Safety)
Old Dominion University
01.2022 - 12.2024
- Trained 25+ teaching assistants in lab safety and procedures, enhancing overall regulatory compliance and safety awareness
- Maintained compliance with environmental safety and hazardous waste protocols, safeguarding lab and community health
- Coordinated chemical preparation and logistics for 25+ lab sections per semester, supporting seamless lab operations
Teaching Assistant
Old Dominion University
08.2021 - 12.2024
- Facilitated lab instruction for 200+ students, promoting safety and procedural compliance
- Addressed experimental and procedural challenges in real time to sustain lab operations
- Assisted professors with classroom management and lesson preparation.
- Facilitated student discussions to enhance understanding of course materials.
- Graded assignments and provided constructive feedback to students.
Mentor (Research Experience for Undergraduates Program)
Old Dominion University
05.2023 - 08.2023
- Trained undergraduate researchers on computational chemistry tools and MD simulation workflows to enhance research capabilities
- Developed structured guidance for new researchers to streamline onboarding process
Undergraduate Researcher
Old Dominion University
01.2018 - 05.2020
- Executed molecular dynamics simulations using AMBER to investigate molecular interactions
- Prepared reagents and ensured sterile lab conditions to support ongoing experiments
Education
PhD - Chemistry
Old Dominion University
Norfolk, VA12-2026
Master of Science - Chemistry
Old Dominion University
Norfolk, VA12-2025
Undergraduate - Biochemistry and Biology
Old Dominion University
Norfolk, VA05-2020
Skills
- Molecular Modeling & Simulation: AMBER, molecular dynamics workflows
- Computational Chemistry: AutoDock, Antechamber, AlphaFold
- Data Analysis & Visualization: VMD, PyMOL, UCSF Chimera
- Technical Environment: Linux, BASH, scripting workflows
- Laboratory & Compliance: Chemical safety (ES&H), lab operations, PPE protocols
- Collaboration: Cross-functional research teams, mentoring, training
Accomplishments
- Recipient of SMART Scholarship (2024)
- Recipient of ORISE Fellowship (2024)
- Presented research at multiple national scientific conferences (ACS)
- Contributed to federally aligned research at ERDC
Selected Research And Publications
Investigated thyroxine binding mechanisms using computational modeling, Tran-Thompson, A.T. et al., Scientific Reports, 2020, Protein–ligand interaction modeling in lysozyme mutants, Structural analysis of EWS-FLI1 fusion protein (Ewing Sarcoma), Cold-adaptation mechanisms in antifreeze proteins
Core Skills
AMBER, VMD, molecular dynamics workflows, AutoDock Vina, Antechamber, AlphaFold, PyMOL, UCSF Chimera, Chemical safety (ES&H), lab operations, PPE protocols, Linux, scripting workflows, Cross-functional research teams, mentoring, training, English (fluent), Vietnamese (fluent)
Timeline
Research Assistant
U.S. Army Corps of Engineers
05.2024 - Current
Mentor (Research Experience for Undergraduates Program)
Old Dominion University
05.2023 - 08.2023
Preparatory Teaching Assistant (Lab Operations & Safety)
Old Dominion University
01.2022 - 12.2024
Teaching Assistant
Old Dominion University
08.2021 - 12.2024
Graduate Researcher (Computational Chemistry)
Old Dominion University
08.2020 - Current
Undergraduate Researcher
Old Dominion University
01.2018 - 05.2020
PhD - Chemistry
Old Dominion University
Master of Science - Chemistry
Old Dominion University
Undergraduate - Biochemistry and Biology
Old Dominion University